2025-08-26
Common side effects of using an insulin pen include: Lipohypertrophy: Lipohypertrophy is a collection of fatty tissue that forms under the skin that occurs due to repeated injections in the same place.
Low blood sugar (hypoglycemia)
Most common side effectSymptoms: shakiness, sweating, dizziness, confusion, rapid heartbeatCaused by taking too much insulin, skipping meals, or intense exercise
Weight gain
Insulin helps store glucose, which can contribute to weight gain over time
Injection site reactions
Redness, swelling, or itching where insulin is injected
Usually mild and temporary
Lipodystrophy (long-term use)
Fatty lumps or indentations can develop at injection sites if the site is not rotated properly
Allergic reactions (rare)
Itching, rash, or more serious allergic responses to insulin or pen components
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